- Sabara, Daryl
- Sandler, Adam
- Sands, Julian
- Sarsgaard, Peter
- Savalas, Telly
- Sawa, Devon
- Schiff, Richard
- Schneider, Rob
- Schwartzman, Jason
- Schwarzenegger, Arnold
- Schweiger, Til
- Schwimmer, David
- Scott, Campbell
- Scott, Dougray
- Scott, Seann William
- Seagal, Steven
- Seinfeld, Jerry
- Selleck, Tom
- Sellers, Peter
- Serbedzija, Rade
- Sewell, Rufus
- Shalhoub, Tony
- Shandling, Garry
- Shanks, Michael
- Sharif, Omar
- Shatner, William
- Sheen, Charlie
- Sheen, Martin
- Sheen, Michael
- Shetty, Sunil
- Short, Martin
- Simmons, Henry
- Sisto, Jeremy
- Slater, Christian
- Smith, Gregory
- Smith, Kevin
- Smith, Kevin
- Smith, Will
- Snipes, Wesley
- Somerhalder, Ian
- Sorbo, Kevin
- Spacey, Kevin
- Spade, David
- Spader, James
- Sparks, Hal
- Speedman, Scott
- Spiner, Brent
- Stahl, Nick
- Stallone, Sylvester
- Stamos, John
- Stamp, Terence
- Statham, Jason
- Stefano, Joey
- Stein, Ben
- Stewart, French
- Stewart, Jon
- Stewart, Patrick
- Stiles, Ryan
- Stiller, Ben
- Stiller, Jerry
- Stockwell, Dean
- Stoltz, Eric
- Stone, Oliver
- Strasberg, Lee
- Sumpter, Jeremy
- Sutherland, Donald
- Sutherland, Kiefer
- Swayze, Patrick
- Sydow, Max Von
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