- Mac, Bernie
- MacLachlan, Kyle
- Macy, William H.
- Madden, Joel
- Maguire, Tobey
- Mahoney, John
- Majors, Lee
- Malkovich, John
- Mantegna, Joe
- Marin, Cheech
- Marsden, James
- Marsters, James
- Martin, Dean
- Martin, Steve
- Martin, Tony
- Martino, Al
- Masterson, Danny
- Mathison, Cameron
- McCarthy, Andrew
- McCartney, Jesse
- McCognauhey, Matthew
- McCormack, Eric
- McDermott, Dylan
- McDermott, Shane
- McDiarmid, Ian
- McDowall, Roddy
- McGregor, Ewan
- McKellen, Ian
- McKenzie, Benjamin
- Mcmahon, Julian
- McQueen, Steve
- Metcalfe, Jesse
- Miller, Larry
- Modine, Matthew
- Mohr, Jay
- Molina, Alfred
- Momoa, Jason
- Monaghan, Dominic
- Moore, Roger
- Moore, Shemar
- Morrow, Rob
- Mortensen, Viggo
- Morton, Joe
- Mos Def
- Mr. T
- Mulroney, Dermot
- Muniz, Frankie
- Murciano, Enrique
- Murphy, Cillian
- Murphy, Eddie
- Murray, Bill
- Murray, Chad Michael
- Myers, Mike
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